All cells need nicotinamide adenine dinucleotide (NAD+), a bioenergetic molecule, to carry out essential functions and for survival. But NAD+ production (biosynthesis) is often elevated in human cancers, where it...
When our livers get injured, whether from chronic alcohol use or the buildup of cellular stress in the form of damaging molecules called reactive oxygen species, it can cause scarring,...
The transplantation of cells found in the bone marrow called mesenchymal stem cells (MSCs), which are important for repairing muscle tissues, is a promising therapy. In particular, MSCs have some...
Japanese scientists have shown that drops containing the NAD+ precursors, NMN or NR, enhance eye gland oily secretions to prevent dry eye disease. Within our eyelids are tiny glands that...
Increasing NAD+ levels with nicotinamide mononucleotide (NMN) improves the defective clearance of damaged mitochondria caused by prion diseases, protecting these neurons from cell death. Prion diseases, which caught the public...
Nicotinamide mononucleotide (NMN) improved photoreceptor cell survival by increasing cellular health-promoting and antioxidant enzyme levels. Age-related eye disorders, such as age-related macular degeneration, diabetic retinopathy, and retinal detachment, often lead...
Treatment of cells modeling dry eye disease with NMN improves their viability by dampening inflammatory marker activation. Dry eye disease is one of the most prevalent eye disorders and causes...
Sirtuin proteins are not required for the NAD+ precursor nicotinamide riboside to enhance liver regeneration. Our livers are constantly fighting off damage. To win this war and keep our body...
Treating immature mouse fat cells with nicotinamide mononucleotide (NMN) improves metabolism and inflammation-related gene activity. As obesity becomes more prevalent globally, so too comes the rising incidence of age-related diseases...
University of Cambridge researchers treat age-related memory loss by maintaining this brain fabric using viral-mediated gene therapy. The brain is like a 3D roadway where electrochemical information gets shuttled to...
Distinguishing these concepts can help guide how to live longer and for more years in good health. Living longer and living more years looking and feeling youthful and disease-free are...
Our cells depend on nicotinamide adenine dinucleotide (NAD+) to function and survive. Drops in NAD+ levels caused by aging are linked to diseases like metabolic disorders, cancer, and neurodegenerative conditions....
Nicotinamide mononucleotide (NMN) has been shown as safe in the short-term (up to six weeks); however, longer-term studies are required to prove safety. Research shows that nicotinamide mononucleotide (NMN) boosts...
NMN treatment improves brain associated blood vessel cell survival and protects against harmful stress in metabolic disorders like diabetes. Diabetes cases continue to rise sharply worldwide. These patients are more...
The reagent nicotinamide mononucleotide (NMN) docks onto the nucleosome assembly protein 1 like-2 (NAP1L2) to reinvigorate the “stemness” of bone mesenchymal stem cells. The breakdown and generation of new bone...
