Cisplatin Induces Cancer Patient Hearing Loss

Cisplatin and similar platinum-based drugs are prescribed for an estimated 10 to 20% of all cancer patients. The drugs cause permanent hearing loss in 40 to 80% of adult patients and at least half of the children who receive the drug. To reduce cisplatin-induced ototoxicity, many challenges remain, including a lack of understanding of how cisplatin causes ototoxicity, and the selection of an optimal treatment strategy has yet to be determined.
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